Norbert Müller Selected Research

Giardiasis

1/2022	3-nitroimidazo[1,2-b]pyridazine as a novel scaffold for antiparasitics with sub-nanomolar anti-Giardia lamblia activity.
1/2018	Physiological aspects of nitro drug resistance in Giardia lamblia.
9/2017	The single cyclic nucleotide-specific phosphodiesterase of the intestinal parasite Giardia lamblia represents a potential drug target.
8/2015	Comparative characterisation of two nitroreductases from Giardia lamblia as potential activators of nitro compounds.
8/2013	Metabolism of nitro drugs metronidazole and nitazoxanide in Giardia lamblia: characterization of a novel nitroreductase (GlNR2).
12/2007	Characterization of a Giardia lamblia WB C6 clone resistant to the isoflavone formononetin.
3/2003	Interleukin-6-deficient mice are highly susceptible to Giardia lamblia infection but exhibit normal intestinal immunoglobulin A responses against the parasite.

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Norbert Müller Research Topics

Disease

52	Schizophrenia (Dementia Praecox) 01/2019 - 06/2002
17	Inflammation (Inflammations) 12/2021 - 06/2002
15	Infections 10/2021 - 02/2003
9	Mental Disorders (Mental Disorder) 01/2021 - 01/2004
7	Giardiasis 01/2022 - 03/2003
7	Tourette Syndrome (Tourette's Syndrome) 01/2014 - 12/2002
5	Major Depressive Disorder (Major Depressive Disorders) 01/2021 - 07/2013
4	Echinococcosis (Hydatid Cysts) 01/2014 - 05/2008
4	Overweight 01/2012 - 01/2008
3	Tics (Tic) 01/2022 - 07/2008
3	Psychotic Disorders (Schizoaffective Disorder) 01/2020 - 01/2017
3	Alveolar echinococcosis 01/2020 - 05/2015
3	Cognitive Dysfunction 07/2017 - 10/2007
3	Weight Gain 10/2008 - 04/2007
2	Tic Disorders (Tic Disorder) 01/2022 - 01/2019
2	Diarrhea 01/2020 - 10/2019
2	Parasitic Diseases (Parasitic Disease) 01/2020 - 05/2015
2	Dementia (Dementias) 01/2019 - 04/2007
2	Bipolar Disorder (Manic Depressive Psychosis) 01/2019 - 03/2016
2	Neurobehavioral Manifestations 07/2017 - 10/2011
2	Postpartum Depression (Post-Natal Depression) 01/2016 - 10/2014
2	Bacterial Infections (Bacterial Infection) 08/2014 - 08/2012
2	Virus Diseases (Viral Diseases) 08/2012 - 08/2012
2	Neoplasm Metastasis (Metastasis) 11/2010 - 02/2006
2	Neoplasms (Cancer) 02/2006 - 08/2004
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2022
1	Lyme Disease (Disease, Lyme) 10/2021
1	Skin Diseases (Skin Disease) 01/2021
1	Epidermolysis Bullosa 01/2021
1	Mood Disorders (Mood Disorder) 01/2021
1	Toxocariasis 02/2019
1	Ascariasis 02/2019
1	Filariasis 02/2019

Drug/Important Bio-Agent (IBA)

23	Antipsychotic Agents (Antipsychotics)IBA 01/2020 - 06/2002
14	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2019 - 01/2004
13	CytokinesIBA 01/2019 - 06/2002
12	Tryptophan (L-Tryptophan)FDA Link 01/2021 - 07/2006
10	Pharmaceutical PreparationsIBA 01/2022 - 06/2002
10	Celecoxib (Celebrex)FDA Link 01/2021 - 06/2002
10	KynurenineIBA 01/2021 - 07/2006
10	N-Methylaspartate (NMDA)IBA 04/2013 - 07/2006
9	Proteins (Proteins, Gene)FDA Link 05/2015 - 02/2003
9	Kynurenic Acid (Kynurenate)IBA 04/2013 - 01/2008
8	AntigensIBA 02/2019 - 01/2004
8	EnzymesIBA 06/2012 - 07/2006
7	Therapeutic UsesIBA 01/2020 - 08/2004
7	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 06/2012 - 01/2008
6	Risperidone (Risperdal Consta)FDA LinkGeneric 09/2007 - 06/2002
5	Interleukin-6 (Interleukin 6)IBA 12/2021 - 02/2004
5	nitazoxanide (NTZ)FDA Link 01/2018 - 01/2006
5	Metronidazole (Metric)FDA LinkGeneric 01/2018 - 01/2006
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 03/2016
4	AntibodiesIBA 02/2019 - 08/2010
4	Quetiapine Fumarate (Seroquel)FDA Link 10/2007 - 12/2005
3	Interleukin-10 (Interleukin 10)IBA 01/2019 - 08/2012
3	Complement System Proteins (Complement)IBA 12/2015 - 02/2007
3	LipopolysaccharidesIBA 08/2014 - 08/2012
3	DNA (Deoxyribonucleic Acid)IBA 01/2014 - 06/2004
3	ProstaglandinsIBA 01/2012 - 08/2004
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 12/2008 - 07/2006
3	Serotonin (5 Hydroxytryptamine)IBA 06/2008 - 08/2004
2	Immunoglobulin G (IgG)IBA 01/2022 - 02/2019
2	Macrophage Migration-Inhibitory FactorsIBA 01/2021 - 09/2006
2	Nitro CompoundsIBA 01/2020 - 01/2018
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2019 - 03/2016
2	ChemokinesIBA 10/2018 - 01/2014
2	Interleukin-4 (Interleukin 4)IBA 10/2018 - 03/2006
2	Drinking WaterIBA 09/2017 - 06/2004
2	Biological ProductsIBA 08/2017 - 12/2002
2	Ribosomal DNA (rDNA)IBA 04/2017 - 05/2007
2	Tuberculin (PPD)IBA 01/2016 - 10/2014
2	Formaldehyde (Formol)FDA Link 12/2015 - 02/2007
2	ParaffinIBA 12/2015 - 02/2007
2	NitroimidazolesIBA 08/2015 - 08/2013
2	Neurotransmitter Agents (Neurotransmitter)IBA 02/2010 - 08/2004
2	Quinolinic AcidIBA 01/2010 - 06/2008
2	Dinoprostone (PGE2)FDA Link 01/2010 - 08/2004
2	Glutamic Acid (Glutamate)FDA Link 12/2008 - 08/2004
2	Phosphates (Orthophosphate)IBA 02/2007 - 02/2003
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2005 - 10/2002
1	pyridazineIBA 01/2022
1	CholesterolIBA 12/2021
1	discoidin-binding polysaccharideIBA 10/2021
1	Carrier Proteins (Binding Protein)IBA 10/2021
1	DecorinIBA 10/2021
1	Sertraline (Zoloft)FDA LinkGeneric 01/2021
1	Ribosomal Proteins (Ribosomal Protein)IBA 01/2021
1	3-hydroxykynurenineIBA 01/2021
1	MicroRNAs (MicroRNA)IBA 01/2020
1	NitroreductasesIBA 10/2019
1	Antidepressive Agents (Antidepressants)IBA 01/2019
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2019
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2019
1	Interferon-gamma (Interferon, gamma)IBA 10/2018
1	Immunoglobulin M (IgM)IBA 08/2017

Therapy/Procedure

22	Therapeutics 01/2020 - 06/2002
3	Deep Brain Stimulation 01/2014 - 07/2008
2	Immunotherapy 10/2018 - 05/2015
2	Drug Therapy (Chemotherapy) 12/2007 - 06/2004
1	Immunomodulation 01/2019